Nanomedicine formulations for combination therapies

Abstract

Nanomedicine formulations are nanometer-sized carrier materials designed for improving the biodistribution of systemically applied (chemo-) therapeutic drugs. Clinically relevant examples of nanomedicine formulations are liposomes, polymers and micelles. By delivering pharmacologically active agents more selectively to pathological sites (site-specific drug delivery) and/or by guiding them away from potentially endangered healthy tissues (site-avoidance drug delivery), nanomedicine formulations aim to improve the balance between the efficacy and the toxicity of therapeutic interventions.

(Published: 8 November 2010)

Citation: Nano Reviews 2010, 1: 5705 - DOI: 10.3402/nano.v1i0.5705